Cognitive Enhancing Nootropics

Table of Contents



Adrafinil is a mild stimulant Nootropic that enhances alertness, concentration, energy, and supports cognitive function.  Despite it's long lasting stimulating effects, Adrafinil does not cause hyperactivity.  Discovered in 1974 by two French chemists, it was first tested on Humans to specifically treat narcolepsy.  It's effects are very similar to Modafinil; however, less potent due to the time for the metabolite to accumulate to active levels in the bloodstream.  Adrafinil acts on the adrenergic system, which is the part of the nervous system that releases adrenaline.  Rapid release of adrenaline leads to an increase of both energy and alertness.  Studies have also found that Adrafinil stimulates the release of serotonin, which is responsible for enhancing mood and reducing anxiety.  


-Promotes wakefulness.

-Alertness and focus.

-Increased aspects of motivation and problem solving.

-Tolerance does not build up quickly.

-No noticeable crash.

-Increased physical performance

Recommended dosage is 300 mg-600 mg and it is recommended to cycle off Adrafinil for a week break after 3 weeks of daily use to reset tolerance.

Full Adrafinil review here

Alpha GPC

Alpha GPC is or also known as alpha-glycerlyphorylcholine, choline alfoscerate, is a naturally occurring compound in the brain that can be synthesized into supplement form and taken as a Nootropic.  Alpha GPC can also be found in many of the foods that we eat on a daily basis such as, eggs, fish, meat, and dairy.  Synthetic Alpha GPC enhances and speeds up choline production to the brain, which leads to enhanced cognition, promotes long term brain health, and in some cases, can increase physical performance.  


-Enhances cognition

-Supports brain health

-Increased physical performance

-Safe for most people and widely available

Recommended dosage ranges between 250 mg-1200 mg per day.

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Bacopa Monnieri

Bacopa Monnieri is a natural perennial herb, that is native to the wetlands of India, Australia, Asia, South America, and parts of Europe.  It is commonly referred to as water hyssop.  Bacopa Monnieri in supplement form has been used as a Nootropic to improve cognition and reduce anxiety.   It's main mechanisms are bacosides A and bacosides B.  Both bacosides help rebuild damaged neurons and they improve the signaling of electrical impulses between neurons in the brain. This ultimately boosts memory and overall brain health.


-Enhances cognition.

-Reduces anxiety and stress.

-Increased motivation and problem solving.

Dosage varies, but recommended is 300 mg-350 mg daily, but this is assuming that the total bacoside content is 55% of the extract by weight.  

Full Bacopa Monnieri review here

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CDP Choline


CDP Choline or also known as Citicoline, is a popular memory enhancing Nootropic.  The supplement acts by creating more acetylcholine in the brain, which is the learning neurotransmitter.  It also repairs neurons in the brain, which has been linked to an overall improvement of memory.  Some of the other very noticeable cognitive effects can range from an increase in focus, mental energy, and quicker learning capabilities.  CDP Choline also stacks incredibly well with other Nootropics.  This is due to it's ability to raise acetylcholine levels in the brain, which enhances the effects of memory boosting supplements, such as certain racetams.



-Improves memory

-Improves learning capacity

-Supports brain energy

-Improves focus and mental clarity

-Stacks well with other Nootropics

Recommended singled dosage is 250 mg per day.  Higher doses can range from 750 mg-1000 mg per day.  

Full CDP Choline review here

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Huperzine A

Huperzine A is a natural Nootropic derived from the Huperziceae herb.  It is known for it's cognitive enhancing benefits, as it is a potent acetylcholinesterase inhibitor.  Increased levels of acetylcholine promotes memory, learning function, and overall mood.  Huperzine A is also a great brain protectant, as it works to block the NMDA receptor from too much glutamate.  This helps brain cells from being over-activated and helps normalize glutamate levels. The combination of boosting acetylcholine and blocking NMDA receptors promotes a healthy balance of neurochemistry in the brain. 


-Supports cognitive function

-Increases energy

-Improves memory

-Enhances learning ability

-Supports brain health

Recommended dosage is between 50 mgc-200 mgc daily.

Full Huperzine A review here

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L-Tyrosine is an amino acid required for the production of the neurotransmitters dopamine, adrenaline and noradrenaline (also known as norepinephrine).  L-Tyrosine also plays an important role in thyroid function.  It can be found in many of our food sources such as, eggs, meats, fish, and dairy products.  Supplementation increases L-Tyrosine levels, which leads to enhanced cognitive benefits, and an improvement in mood. 


-Improves mood 

-Enhances cognitive function

-Increases energy

-Better mental focus and clarity

-ADHD treatment

-Boosts physical performance

Recommended dosage range is 350 mg-2000 mg daily. 

Full L-Tyrosine review here

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Noopept is a potent cognitive enhancer that is is the Peptide class of Nootropics.  It's mechanisms are very similar to Piracetam, but the effects are up to 1000 times more powerful.  Noopept was first developed in 1970 to protect the brain against oxidative damage.  Since then, it has evolved into a fast-acting, powerful cognitive enhancer in today's world of Nootropics.  


-Boosts memory

-Enhances learning capability

-Increases focus

-Reduces anxiety

-Promotes brain health

-Fast acting

-Long lasting effects

Recommended dosage is 10 mg-30 mg per day and it is recommended to cycle off after 3 months of daily use to reset tolerance.

Full Noopept review here

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Phenylpiracetam is in the synthetic racetam class of Nootropics and has shown to enhance energy, memory, physical performance, and cognition.  It was originally developed in 1983 for the primary purpose of increasing physical and cognitive activities for Russian Cosmonauts in space.  Phenylpiracetam is a very powerful Nootropic that can significally increase locomotor activity even at the smallest dosage.  


-Enhances focus and attention

-Improves memory

-Boosts energy

-Reduces anxiety

-Increased physical performance

Single doses vary between 100 mg-250 mg and should not exceed 750 mg in a 24 hour period.   It is recommended to cycle Phenylpiracetam 2-3 days a week when needing an extra energy boost.  

Full Phenylpiracetam review here

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Phenibut is a Nootropic compound that was originally developed in Russia in the 1960's to treat anxiety and depression.  It is derived from the neurotransmitter GABA.  It has anxiolytic and cognitive enhancing effects by acting as a GABA-mimetic on both GABA A and GABA B receptors. Effects are very powerful, as the supplement stimulates dopamine receptors, which can directly enhance mood, focus, and motivation.


-Promotes a feeling of calm

-Reduces anxiety

-Increases cognition

-Increases physical performance

-Improves sleep

-Increased libido

-Long lasting effects

Recommended dosage is 600 mg-1200 mg, and should only be taken a maximum of 1-2 times per week.

Full Phenibut review here

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